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Small Mammals + Medications

  • Marbofloxacin is given by mouth and is used on and off label to treat certain bacterial infections including leishmaniasis, tuberculosis, and hemoplasmosis. Common side effects include vomiting, diarrhea, and lack of appetite. Do not use in pets that are allergic to it or other quinolones, or in small and medium breed dogs before 8 months of age, in large breed dogs before 12 months of age, in giant breed dogs before 18 months of age, or in cats before 12 months of age. If a negative reaction occurs, please call your veterinary office.

  • Meclizine is used off label and given by mouth in the form of a tablet to treat and prevent motion sickness and vomiting in dogs, cats, and small mammals. The most common side effect is sedation and sleepiness. Do not use in pets that are allergic to it. It should be used with caution in pets with concurrent prostate enlargement, bladder obstruction, heart failure, certain types glaucoma, or certain gastrointestinal obstructions. If a negative reaction occurs, please call your veterinary office.

  • Melatonin is given by mouth or as an implant under the skin and is used to treat sleep and behavior disorders, adrenal disease, and non-allergic hair loss, to suppress the heat cycle, and to improve breeding rates. Give as directed. Side effects are not common but may include sleepiness. Do not use in pets that are allergic to it. If a negative reaction occurs, please call your veterinary office.

  • Metoclopramide (brand names Reglan® and Maxolon®) is used to off label to treat esophageal reflux, prevent or treat vomiting, stimulate milk-let down, and increase milk production. It is available as an oral tablet, oral liquid suspension, and as an injectable form. Your veterinarian may have you inject metoclopramide under the skin if vomiting is an issue. Metoclopramide may interact with many commonly prescribed drugs so it is important to tell your veterinarian about any medications that your pet is currently taking.

  • Nystatin is an antifungal, given by mouth in the form of a tablet or liquid suspension, and used off label to treat Candida fungal infections in dogs, cats, birds, and reptiles. Side effects are rare, but at high doses could cause stomach upset or mouth irritation. It should not be used in pets that are allergic to it. If a negative reaction occurs, please call your veterinary office.

  • Omeprazole (brand names Gastrogard® and Prilosec®) is used to off label to treat ulcers in cats and dogs. It is also used to treat gastritis in dogs and gastroenteritis in ferrets. Side effects to omeprazole are not common, but can include vomiting, decreased appetite, gas, and diarrhea. Other drugs may interact with omeprazole so it is important to tell your veterinarian about any medications or supplements that your pet is taking.

  • Orbifloxacin is given by mouth and is used on and off label to treat certain susceptible bacterial infections. Give as directed by your veterinarian. The most common side effects include vomiting, diarrhea, and lack of appetite. Do not use in pets that are allergic to it or other quinolones, in growing pets, or in conjunction with cyclosporine. If a negative reaction occurs, please call your veterinary office.

  • Phenobarbital is used off label and given by mouth or as an injection to treat seizures or to sedate your pet. Common side effects include sleepiness, increased thirst, urination, and/or appetite. Do not use this medication in pets with liver, lung, or kidney disease or those that are allergic to barbiturates. If a negative reaction occurs, please call your veterinary office.

  • Polysulfated glycosaminoglycan (PSGAG) is given by injection and is used on and off label to treat arthritis and degenerative joint disease. Side effects are uncommon but may include joint pain, joint swelling, vomiting, diarrhea, lack of appetite, or sleepiness. Do not use in pets that are allergic to it, or pets with a known or suspected bleeding disorder. If a negative reaction occurs, please call your veterinary office.

  • Prednisone/prednisolone is given by mouth or injection and is used on and off label to treat Addison’s disease, inflammatory conditions, neoplasia (cancer), and immune-mediated diseases. Give this medication as directed by your veterinarian. Common side effects include increased drinking, increased urination, and increased appetite. Do not use in pets that are allergic to it, or pets with systemic fungal infections, viral infections, ulcers, tuberculosis, or Cushing’s disease. If a negative reaction occurs, please call your veterinary office.

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